When many people first tell someone they have genital herpes, they start by comparing the infection to oral herpes, or cold sores. HSV-1 is usually mild, especially when it infects the lips, face, or genitals. However, she warns, transmission of genital HSV-1 during asymptomatic shedding has been documented. Genital herpes, often simply known as herpes, may have minimal symptoms or form blisters that break open and result in small ulcers. HSV-1 has been proposed as a possible cause of Alzheimer’s disease. Herpes simplex virus type 1 (HSV-1) is usually the cause of oral infection. Viral culture from swabs of lesions has been considered the gold standard but is limited by the short time period of viral shedding and the relatively low number of viral particles present in samples.
HSV has a great impact on human health globally due to its high prevalence, successful sexual transmissibility rate, association with immunocompromised patients, and ability to cause recurrent disease (Miller, AHMF). HSV-1 is considered to be oral-facial herpes (commonly appearing on the lips and nares as cold sores), which is transmitted mostly by oral lesions or secretions. But even though HSV-1 typically causes sores around the mouth and HSV-2 causes genital sores, these viruses can cause sores in either place. The herpes simplex virus-1, which has been lying dormant in the body, reactivates or wakes up. Most individuals infected with HSV-1 or HSV-2 are asymptomatic or have very mild symptoms that go unnoticed or are mistaken for another skin condition. Symptoms of recurrent outbreaks are typically shorter in duration and less severe than the first outbreak of genital herpes. The surest way to avoid transmission of sexually transmitted diseases, including genital herpes, is to abstain from sexual contact, or to be in a long-term mutually monogamous relationship with a partner who has been tested and is known to be uninfected.
The first infection with HSV-1 or oral herpes often causes no symptoms but it may cause sores in the mouth around the teeth and gums ( gingivostomatitis ). There are also specific blood tests which can be helpful in some patients to figure out which virus type caused the symptoms or to figure out if one partner has been infected by herpes. Herpes simplex virus type 1 (HSV-1) typically causes infection above the waist and the infections are localized to mouth and oropharynx, whereas herpes simplex virus type 2 (HSV-2) usually causes genital infections and can also cause CNS or disseminated disease in neonates. Dysfunction of the autonomic nervous system and transverse myelitis has been associated with genital herpes simplex virus infection. Is it true that if you already have hsv-1 (mouth cold sores) you cant get it down south? Had it just been asymptomatic shedding (a lower level of the virus than an active sore), my antibodies may well have protected me. So, overall HSV1 genitally is better than HSV2, its typically more mild, occurs less often, and has less chance of transmission.
What Are HSV-1 And HSV-2?
HSV-1 generally occurs above the waist (e.g., a cold sore on the lip). HSV-1 is generally associated with infections in and around the mouth and with other infections above the waist. These vesicles break and form a crust, and the skin appears normal within 6 to 10 days after the onset of the lesion, unless there has been secondary infection. (4) Similar HSV prevalences have been reported in Europe, and even higher seroprevalences have been seen in many parts of the developing world. HSV reactivation among the HIV-1-infected typically presents with vesicular and ulcerative lesions of the oral and anogenital areas. Herpes viruses have been linked to Recurrent Lymphocytic Meningitis (Mollaret’s meningitis), which is characterized by sudden attacks of meningitis symptoms that last for 2-7 days and are separated by symptom-free (latent) intervals lasting for weeks, months or years. HSV-1 (type I) typically infects above the waist and around the mouth developing cold sores. Historical Information: The Herpes Virus has been said to have existed as far back as greek times when greek philosophers say the term herpes meaning to creep or crawl referring to how the disease moved across the skin. Figure 1 shows typical CT and MRI changes in patients with HSV-1 encephalitis compared with imaging abnormalities in VZV vasculopathy (see below) and other viral encephalitides.
HSV-1 is typically oral herpes where HSV-2 is almost always in the genital region. While there have been a few very rare cases, HSV-2 typically does not affect the oral region. Genital herpes is a STI caused by the herpes simplex viruses type 1 (HSV-1) & type 2 (HSV-2). Generally, a person can only get HSV-2 infection during sexual contact with someone who has a genital HSV-2 infection, but you can get herpes from kissing. The surest way to avoid transmission of sexually transmitted diseases, including genital herpes, is to abstain from sexual contact or to be in a long-term mutually monogamous relationship with a partner who has been tested and is known to be uninfected. HSV-1, on the other hand, has historically been commonly transmitted in early childhood, for instance if an infected adult kisses an uninfected child. The viruses are known by numbers as human herpes virus 1 through 8 (HHV1 – HHV8). Like other human herpes viruses, HHV6 and HHV7 are so common that most of humankind has been infected at some point, usually early in life.
HSV-1 is usually the cause of oral infection. However, transmission of genital HSV-1 during asymptomatic shedding has been well documented.